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Test clinici


Effect of a ginger extract on pregnancy-induced nausea: A randomised controlled trial

Test a doppio cieco effettuato su 120 donne al di sotto della 20ma settimana di gravidanza, che hanno sofferto di nausee mattutine quotidiane per almeno una settimana e che non hanno rilevato nessun miglioramento dei sintomi con la semplice variazione della propria dieta.
Risultati: Il sintomo della nausea si è significativamente ridotto per il gruppo che ha assunto zenzero rispetto al gruppo placebo, già dal primo giorno di trattamento e tale differenza si è manifestata per tutta la durata del trattamento.[…]
Conclusioni: Lo zenzero può essere considerato un utile trattamento per le donne incinte che soffrono di nausee mattutine.

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Ginger for Nausea and Vomiting in Pregnancy: Randomized, Double-Masked, Placebo-Controlled Trial

Test a doppio cieco della durata d 5 mesi effettuato su 70 donne al di sotto della 17ma settimana di gravidanza, che hanno sofferto di nausee mattutine.
Risultati: Il sintomo della nausea si è significativamente ridotto per il gruppo che ha assunto zenzero rispetto al gruppo placebo. Anche il numero di episodi di vomito è diminuito significativamente nel gruppo che ha assunto zenzero, rispetto al gruppo placebo. Non è stato rilevato alcun effetto collaterale sull’esito della gravidanza.
Conclusioni: Lo zenzero è efficace nell’alleviare nausea e vomito in gravidanza.

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Effects of ginger on motion sickness and gastric slow-wave dysrhythmias induced by circular vection

Ginger has long been used as an alternative medication to prevent motion sickness. The mechanism of its action, however, is unknown. We hypothesize that ginger ameliorates the nausea associated with motion sickness by preventing the development of gastric dysrhythmias and the elevation of plasma vasopressin.

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The Effectiveness of Ginger in the Prevention of Nausea and Vomiting during Pregnancy and Chemotherapy

The rhizomes of Zingiber officinale (ginger) have been used since ancient times as a traditional remedy for gastrointestinal complaints. The most active ingredients in ginger are the pungent principles, particularly gingerols and shogaols. Various preclinical and clinical studies have evaluated ginger as an effective and safe treatment for nausea and vomiting in the context of pregnancy and as an adjuvant treatment for chemotherapy-induced nausea and vomiting.

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Some phytochemical, pharmacological and toxicological properties of ginger (Zingiber officinale Roscoe): a review of recent research.

Ginger (Zingiber officinale Roscoe, Zingiberacae) is a medicinal plant that has been widely used in Chinese, Ayurvedic and Tibb-Unani herbal medicines all over the world, since antiquity, for a wide array of unrelated ailments that include arthritis, rheumatism, sprains, muscular aches, pains, sore throats, cramps, constipation, indigestion, vomiting, hypertension, dementia, fever, infectious diseases and helminthiasis.

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Effect of a ginger extract on pregnancy-induced nausea

Design: Double-blind randomised placebo-controlled trial.
Setting: A tertiary metropolitan teaching hospital, March 1999–November 1999.
Participants: The participants included 120 women less than 20 weeks pregnant, who had experienced morning sickness daily for at least a week and had had no relief of symptoms through dietary changes.

Intervention: Random allocation of 125 mg ginger extract (EV.EXT35; equivalent to 1.5 g of dried ginger) or placebo given four times per day for 4 days.
Main outcome measures: Nausea, vomiting and retching as measured by the Rhodes Index of Nausea, Vomiting and Retching.

Results: The nausea experience score was significantly less for the ginger extract group relative to the placebo group after the first day of treatment and this difference was present for each treatment day. Retching was also reduced by the ginger extract although to a lesser extent. No significant effect was observed on vomiting. Follow-up of the pregnancies revealed normal ranges of birthweight, gestational age, Apgar scores and frequencies of congenital abnormalities when the study group infants were compared to the general population of infants born at the Royal Hospital for Women for the year 1999–2000.

Conclusion: Ginger can be considered as a useful treatment option for women suffering from morning sickness.
Key words: ginger, pregnancy, nausea, Zingiber officinale, morning sickness

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Ginger for Nausea and Vomiting in Pregnancy

Ginger for Nausea and Vomiting in Pregnancy: Randomized, Double-Masked, Placebo-Controlled Trial.
Objective: To determine the effectiveness of ginger for the treatment of nausea and vomiting of pregnancy.

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